Comments on: VEGF Causes Blindness in Diabetes and Macular Degeneration http://www.retinaeyedoctor.com/2009/12/vegf-causes-blindness-in-diabetes-and-macular-degeneration/ Randall V. Wong, M.D., Retinal Specialist Tue, 07 Feb 2012 13:24:53 +0000 hourly 1 http://wordpress.org/?v=3.3.1 By: Intraocular Injections Deliver Drugs Directly to Retinav ` http://www.retinaeyedoctor.com/2009/12/vegf-causes-blindness-in-diabetes-and-macular-degeneration/comment-page-1/#comment-687 Intraocular Injections Deliver Drugs Directly to Retinav ` Sat, 01 May 2010 20:54:47 +0000 http://retinaeyedoctor.com/?p=888#comment-687 [...] beat a dead horse – This is why we are using intraocular injections to deliver steroids and anti-VEGF medications to treat macular degeneration and diabetic retinopathy.  These drugs do not get into the eye via [...] [...] beat a dead horse – This is why we are using intraocular injections to deliver steroids and anti-VEGF medications to treat macular degeneration and diabetic retinopathy.  These drugs do not get into the eye via [...]

]]> By: Randall V. Wong, M.D. http://www.retinaeyedoctor.com/2009/12/vegf-causes-blindness-in-diabetes-and-macular-degeneration/comment-page-1/#comment-340 Randall V. Wong, M.D. Mon, 14 Dec 2009 16:47:14 +0000 http://retinaeyedoctor.com/?p=888#comment-340 Later this week, I'll review the differences between Avastin, Macugen and Lucentis. One of the differences is the different types of VEGF that are blocked. Not all VEGF is bad. Some VEGF is necessary for normal growth and development. Having said that, it seems that it is safe to block most of the VEGF variants in the eye. The drug is short lived, lasting only about 4-8 hours, depending on the drug. This answers your second part, preventative injections probably won't work since the drug isn't in the eye too long. Thanks for reading............and commenting. r Later this week, I’ll review the differences between Avastin, Macugen and Lucentis. One of the differences is the different types of VEGF that are blocked. Not all VEGF is bad. Some VEGF is necessary for normal growth and development. Having said that, it seems that it is safe to block most of the VEGF variants in the eye. The drug is short lived, lasting only about 4-8 hours, depending on the drug. This answers your second part, preventative injections probably won’t work since the drug isn’t in the eye too long.

Thanks for reading…………and commenting.

r

]]> By: Aissa Dirawatun http://www.retinaeyedoctor.com/2009/12/vegf-causes-blindness-in-diabetes-and-macular-degeneration/comment-page-1/#comment-339 Aissa Dirawatun Mon, 14 Dec 2009 16:35:29 +0000 http://retinaeyedoctor.com/?p=888#comment-339 Is there a way to block every single receptor in the retina so wet AMD and/or diabetic retinopathy doesn't occur? Would preventative Avastin injection (for example) help patients with history of wet AMD or early diabetic retinopathy? Is there a way to block every single receptor in the retina so wet AMD and/or diabetic retinopathy doesn’t occur?

Would preventative Avastin injection (for example) help patients with history of wet AMD or early diabetic retinopathy?

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