Alimera Sciences Says Iluvien Effective at 3 Years

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Iluvien, a sustained release drug-delivery system for the treatment of diabetic macular edema, may be getting closer to possible FDA approval.  The parent company, Alimera Sciences has resubmitted additional safety and efficacy data as requested by the FDA last year.  The FDA requested that they be given data extending for a 3 year period instead of the 2 years in the new … [Read more...]

Laser and anti-VEGF Best Treats Diabetic Macular Edema

Laser and anti-VEGF Best Treatment for Diabetic Macular Edema

Treating diabetic retinopathy with both laser and anti-VEGF injections may be the best way to treat patients with diabetic macular edema.  Diabetic macular edema is the most common "side effect" of diabetic retinopathy and is the leading cause of vision loss in patients with diabetes. The results of a large, multicenter, randomized clinical trial compared several … [Read more...]

Diabetes? 4 Things You Need to Know

I tell every new diabetic patient I meet 4 things:  they are going to develop diabetic retinopathy regular eye exams prevent vision loss good sugar control doesn't save them and their other doctors are dead wrong.  It is a message I have developed to hammer home the idea that diabetic retinopathy can be blinding and most doctors don't understand  how this … [Read more...]

Combination Injections for Diabetic Retinopathy

Injecting both Avastin and a steroid injection can be a useful way to treat stubborn macular edema from diabetic retinopathy.  While both can be used alone to treat macular swelling in diabetic patients, the combination is sometimes considered as an alternative. Traditional Laser The gold standard has been to treat diabetic macular edema with laser treatment.  This has … [Read more...]

Vitreous Hemorrhage and Diabetes

A vitreous hemorrhage can result in sudden, painless loss of vision.  In patients with diabetes, the cause may be due to either a posterior vitreous detachment (PVD) or proliferative diabetic retinopathy (PDR).  Remember, the proliferative phase of the diabetic retinopathy means that there are areas of neovascularization (abnormal blood vessel proliferation) on the surface … [Read more...]

Sustained Release; Ozurdex Now Treats Diabetic Macular Edema?

Ozurdex, a sustained release drug delivery system,  may soon be used to treat diabetic macular edema. The sustained release intravitreal implant has been tested, with favorable results, for possible use in treating the common retinal swelling caused by diabetes. Results were published recently in the March issue of the Archives of Ophthalmology. Ozurdex was FDA … [Read more...]

Blurry Vision and Other Symptoms of Diabetes

Blurry vision is a common symptom of diabetes.  Other diabetic symptoms include excessive thirst, frequent urination, weight loss and fatigue.  Most of the symptoms are due to the lack of insulin which secondarily allows the sugar levels to sky rocket out of control.  This sets up sugar gradients that cause imbalances in water distribution in the body and in different … [Read more...]

It’s Not What You Look At, It’s What You Look For

Making a diagnosis can be difficult.  Diabetic retinopathy and macular degeneration are easy to diagnose, but you have to know to look for it to see it.  The diagnosis then becomes pretty obvious.  Knowing what to look for is essential to making a correct medical diagnosis.  Retinal disease, such as ARMD and diabetic retinopathy, is easy to diagnose as we can also "see" … [Read more...]

Macular Degeneration Treatment and the Blood Brain Barrier

The retina is part of the central nervous system.  Delivering medicine into the central nervous system, or to the retina, by traditional means has historically been very difficult; hence the popularity of intraocular injections.  By bypassing the blood-brain-barrier (or blood-retina-barrier), drugs are now effectively delivered to the "target" tissue. The usual methods … [Read more...]

A1C Now Used to Diagnose Diabetes

The American Diabetes Association now recommends basing the diagnosis of diabetes upon the hemoglobin A1C levels and not on fasting glucose tests.  In addition, an A1C of less than 7.0% should be the target for glucose control.  How with this impact the treatment of diabetic retinopathy? The change in recommendations stems from the fact that the A1C blood test is an … [Read more...]

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