Macugen: First anti-VEGF Eye Injection….so, Where’s Waldo?

Like the image game "Waldo," Macugen® seems to be lost in a sea of literature about other anti-VEGF intraocular injections.  Macugen was; however, the first intraocular injection for the treatment of wet macular degeneration.  It became FDA approved for the treatment of wet ARMD in 2004.  Where is it now? The First anti-VEGF Intraocular Injection. Quite simply, this was a significant change … [Read more...]

Eye Injections Challenge Eye Laser for Diabetic Retinopathy

There is a small study just published in the journal "Ophthalmology" stating that intraocular injections of Lucentis® were superior to laser photocoagulation for the treatment of diabetic macular edema.  As you read this, don't forget that the "gold-standard" for treatment of diabetic macular edema is still laser photocoagulation.  These "studies" are very small and not of the caliber needed to … [Read more...]

Shot in the Eye: Safe and…..Painless

Intraocular injections are given all the time. They don't hurt. Intraocular injections of anti-VEGF medications (e.g. Avastin®, Lucentis ®and Macugen®) are given for the treatment of macular degeneration and also, sometimes, diabetic retinopathy. A retinal specialist sees a variety of patients with retina disease, but most of the patients have either macular degeneration or diabetic … [Read more...]

Intraocular Drug System Passing FDA Testing

Earlier this week, I wrote about a device, Iluvien ™, that will release steroid into the eye.  This drug delivery system is manufactured by Alimera Sciences. Read my earlier post "Company Hopes Injectable Implant To Cure Diabetic Macular Edema." Alimera Sciences has announced that early data is showing that the drug system is safe and effective in humans.  The results are preliminary, … [Read more...]

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